| 摘要 |
A composition of matter is provided having a mixture of active estrogenic compounds. The mixture is present in chemically pure form. The mixture includes salts of conjugated estrone, conjugated equilin, conjugated Delta<8,9>-dehydroestrone, conjugated 17alpha-estradiol, conjugated 17alpha-dihydroequilin, conjugated 17beta-dihydroequilin, conjugated 17beta-estradiol, conjugated equilenin, conjugated 17alpha-dihydroequilenin, and conjugated 17beta-dihydroequilenin. The mixture also contains the same essential estrogenic compounds present in naturally derived equine conjugated estrogens. Drug products including the composition of matter are also provided, as are methods of using these drug products to treat mammals in need of treatment. Methods of analyzing mixtures containing conjugated estrogens are also provided. |
