发明名称 Novel crystal of stilbene derivative and process for producing the same
摘要 A Type IV crystal of (Z)-N-Ä2-methoxy-5-Ä2-(3,4,5-trimethoxyphenyl)vinylÜphenylÜ-L-serinamide hydrochloride, which can be produced at a crystallization step using a solvent containing water at 2 % by weight at the maximum and which has a X ray powder diffraction pattern with peaks containing at least those at 13.4 DEG , 18.7 DEG , 19.4 DEG and 22.5 DEG (2&thetas;) is provided. This compound is useful as an effective ingredient for a carcinostatic agent. In accordance with the present invention, a crystal is obtained, which has excellent properties desirable from the standpoint of the production of medicinal products, i.e. exceedingly less water adsorption and extremely high stability to water. Also provided are a method for producing the Type IV crystal thereof and a method for use of the crystal. <IMAGE>
申请公布号 AU4114001(A) 申请公布日期 2001.09.24
申请号 AU20010041140 申请日期 2001.03.14
申请人 AJINOMOTO CO. INC. 发明人 SHINICHIRO TAKAHASHI;YOKO SUGAWARA;HIROYUKI MATSUEDA
分类号 A61K31/167;A61P35/00;C07C231/24;C07C237/08 主分类号 A61K31/167
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