NOVEL PROCESS FOR THE PREPARATION OF A QUINOLINE CARBOXYLIC ACID DERIVATIVE HAVING A 7-(4-AMINOMETHYL-3-OXIME)PYRROLIDINE SUBSTITUENT

摘要

The present invention relates to a novel process for preparing quinoline carboxylic acid antimicrobials having a 7-(4-aminomethyl-3-oxime)pyrrolidine substituent, e.g. gemifloxacin, or salt thereof, wherein a specific surfactant is used so that the filtration time can be significantly reduced compared with the prior art method.