发明名称 |
PH SENSITIVE MRI CONTRAST AGENTS |
摘要 |
A composition and method is disclosed for providing a magnetic resonance imaging contrast agent that is sensitive to pH, the compound and salts thereof including, a tetraaza base having a spacer at each of the amide groups, and a proton exchange attached to each of the spacer molecules, wherein the proton exchange group groups mediate proton exchange with water molecules that are trapped within the tetraaza base molecule.
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申请公布号 |
WO0047111(A9) |
申请公布日期 |
2001.09.20 |
申请号 |
WO2000US03283 |
申请日期 |
2000.02.09 |
申请人 |
BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM;SHERRY, A., DEAN;ZHANG, SHANRONG;WU, KUANGCONG |
发明人 |
SHERRY, A., DEAN;ZHANG, SHANRONG;WU, KUANGCONG |
分类号 |
A61K49/06;(IPC1-7):A61B5/055 |
主分类号 |
A61K49/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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