| 发明名称 |
APO-A-I REGULATION OF T-CELL SIGNALING |
| 摘要 |
The invention provides AFTI polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing AFTI polypeptides. Also provided are methods for the treatment, diagnosis, amelioration, or prevention of diseases with AFTI polypeptides, particularly IL-1 mediated diseases, TNF- alpha mediated diseases, and diseases involving monocyte activation.
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| 申请公布号 |
WO0168852(A2) |
申请公布日期 |
2001.09.20 |
| 申请号 |
WO2001US07826 |
申请日期 |
2001.03.13 |
| 申请人 |
AMGEN INC. |
发明人 |
EDWARDS, CARL, K., III;BURGER, DANIELLE;DAYER, JEAN-MICHEL;KOHNO, TADAHIKO |
| 分类号 |
C12N15/09;A61K38/00;A61K45/00;A61P29/00;A61P37/04;A61P43/00;C07K14/47;C07K14/775;C07K16/18;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;(IPC1-7):C12N15/12;C12N15/62;C12N15/86;C12N5/12;A61K38/17;G01N33/577;G01N33/68 |
主分类号 |
C12N15/09 |
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