| 摘要 |
Compounds useful for alleviating symptoms of depression are provided which have the following formula:wherein:R1 is hydrogen, lower alkyl or aryl;R2 is hydrogen, lower alkyl, phenyl or substituted phenyl;X and Y are each, independently, hydrogen, lower alkyl, lower alkoxy, or halogen, or together combine with the carbon atoms to which they are attached to complete a cyclopentyl, cyclohexyl, phenyl, pyrrolyl, pyranyl, pyridinyl, dihydrofuranyl, furanyl, dioxanyl, oxazolyl or isoxazolyl group;Z is hydrogen, halogen or lower alkoxy; with the proviso that when X, Y or Z represent lower alkoxy, they are not present at the ortho position;W is hydrogen, halogen, lower alkyl, cyano or a trifluoromethyl group; andn is 2-5; orpharmaceutically acceptable salts thereof.
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