摘要 |
In the production of N-benzyldioxothiazolidinylmethyl-benzamide derivatives useful in the treatment of diabetes and hyperlipidemia, it is necessary to develop novel intermediates for the production on an industrial scale of 5-formyl-2-methoxybenzoate esters, which are used as starting materials in producing the derivatives, and processes for production of the esters with the intermediates. It has been found that 4-methoxy-3-alkoxycarbonylphenyl-methylhexamethylenetetraminium chlorides represented by the general formula (1) (wherein R is lower alkyl) are useful as intermediates in the production of 5-formyl-2-methoxybenzoate esters on an industrial scale. |