发明名称 |
Design, synthesis and use of affinity ligands |
摘要 |
An affinity ligand is constructed from at least 3 domains: (1) a recognition domain, e.g. a 3-6 amino acid chain specific for a peptide region of a target; this may be discovered and/or optimised by fitting candidate structures or parts thereof to a model of the target in a computer memory; (2) an affinity domain, e.g. a domain capable of binding to a particular type of region of the target such as a glycosylation region; and (3) a flexible linker having a functional group enabling the ligand to be immobilised to a sensor surface to create a specific biosensor. |
申请公布号 |
AU4078301(A) |
申请公布日期 |
2001.09.17 |
申请号 |
AU20010040783 |
申请日期 |
2001.03.08 |
申请人 |
CRANFIELD UNIVERSITY |
发明人 |
BEINING CHEN;RICHARD MICHAEL DAY;KHALKU KARIM;ANTHONY PETER FRANCIS TURNER |
分类号 |
C07K7/64;C07K14/00;C07K14/705;G06F19/16 |
主分类号 |
C07K7/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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