| 摘要 |
Preparation of citalopram comprises the steps of: (a) converting the compound of Formula (I) to a compound of Formula (II), wherein R in Formula (I) represents a C<SUB>2 </SUB>to C<SUB>5 </SUB>alkylene group which may be substituted or unsubstituted, and R<SUP>1 </SUP>in the compounds of Formula (II) represents a carboxylic acid group or a salt or an ester thereof; and (b) converting the compound of Formula (II) to form citalopram or a pharmaceutically acceptable salt thereof, or a direct conversion of the compound of Formula (I) to citalop |
