METHOD OF ANTICIPATING INTERACTION BETWEEN PROTEINS

摘要

A method of anticipating an interaction between proteins characterized by comprising: (1) digesting the amino acid sequence of a protein A to give oligopeptides of certain length; (2) searching for a protein C having the above-described oligopeptides or a protein D having oligopeptides homologous with the above-described oligopeptides from a protein data base; (3) performing local alignment between the above-described protein A and the protein C or D thus detected; and (4) anticipating that the detected protein C or D is a protein B having an interaction with the protein A by using a value calculated from the amino acid frequencies or oligopeptide frequencies based on the results of the local alignment and the protein data base; a recording medium carrying the above anticipation program; an anticipation apparatus carrying this recording medium; and proteins obtained therefrom.