METHOD FOR PRODUCING N-ARYL-AZA-HETEROCYCLES IN THE PRESENCE OF CESIUM CARBONATE

摘要

The invention relates to a method for producing N-aryl-aza-heterocycles of general formula (I) in which: R1, R2, R3, R4 and R5 are the same or different and represent a hydrogen atom, a nitro group, a cyano group, an alkoxycarbonyl group with up to 5 C atoms, an aldehyde group, an alkylcarbonyl group with up to 5 C atoms, an arylcarbonyl group or an amide group, whereby the radicals R1 to R5 can not all be a hydrogen atom at the same time, and; HETN represents an aromatic aza-heterocycle with 5 or 6 ring atoms, whereby up to 3 ring atoms can be nitrogen atoms, and up to two additional aromatic carbon rings can be fused to the heterocycle. The inventive N-aryl-aza-heterocycles are produced by reacting, at room temperature, aza-heterocycles with activated aromatic compounds of general formula (XIV), in which HAL represents a halogen atom, while using cesium carbonate and without adding additional catalysts.