alpha -SUBSTITUTION OF UNPROTECTED beta -AMINO ESTER COMPOUNDS

摘要

Methods for stereoselective substitution in which a (mono or un)- alpha -substituted unprotected beta -amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium compounds, lithium hybride, lithium amide, lithium dialkyl amides and alkali hexamethyldisilylamines.