发明名称 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-<i>de</i>]ACRIDONES WITH ANTI-TUMOR ACTIVITY
摘要 The invention provides imidazoacridone compounds of general formula (1) which have cytotoxic and anti-tumor activity. The invention also provides methods of preparing the compounds, and methods of using the compounds for the treatment of cancer or other mammalian diseases characterized by undesirably high levels of cell proliferation. The compounds of the invention are also expected to have utility as research tools.
申请公布号 WO0166545(A2) 申请公布日期 2001.09.13
申请号 WO2001US07087 申请日期 2001.03.05
申请人 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;CHOLODY, WIESLAW, M.;KOSAKOWSKA-CHOLODY, TERESA;MICHEJDA, CHRISTOPHER, J. 发明人 CHOLODY, WIESLAW, M.;KOSAKOWSKA-CHOLODY, TERESA;MICHEJDA, CHRISTOPHER, J.
分类号 A61K31/4745;A61K31/496;A61K31/506;A61P35/00;C07D471/06;(IPC1-7):C07D471/06;A61K31/437 主分类号 A61K31/4745
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