摘要 |
<p>A factor capable of attracting and activating neutrophils which might be prepared by normal cells. A polypeptide having an activity of stimulating neutrophils is isolated from an extract obtained from healthy swine heart. Namely, provision is made of: (a) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:1; (b) a polypeptide comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO:1 by deletion, substitution or insertion of one to several amino acids and having the activity of stimulating neutrophils; and (c) a polypeptide comprising an amino acid sequence which is biologically equivalent to the amino acid sequence of the polypeptide (a) or (b) as described above.</p> |