发明名称 |
PREDISPOSITION TO BREAST CANCER BY MUTATIONS AT THE ATAXIA-TELANGIECTASIA GENETIC LOCUS |
摘要 |
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to the discovery that some alleles of the A-T gene cause susceptibility to cancer, in particular breast cancer. More specifically, the present invention relates to germline mutations in the A-T gene and their use in the diagnosis of predisposition to breast cancer. The invention further relates to somatic mutations in the A-T gene in human breast cancer and their use in the diagnosis and prognosis of human breast cancer.
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申请公布号 |
US2001021502(A1) |
申请公布日期 |
2001.09.13 |
申请号 |
US19970984090 |
申请日期 |
1997.12.03 |
申请人 |
SWIFT MICHAEL R.;ATHMA PRASANNA;LI AIRONG |
发明人 |
SWIFT MICHAEL R.;ATHMA PRASANNA;LI AIRONG |
分类号 |
C07K16/18;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04;C12P19/34 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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