发明名称 PYRROLCARBOXAMIDES
摘要 <p>Disclosed are compounds of general formula (III), wherein R1 is phenyl, optionally substituted by fluor, chlorine or bromine; R2 and R3 are independently hydrogen atom, alkyl with C1-6, phenyl, optionally substituted by fluor, chlorine or bromine, or group of general formula -CONR5R6, wherein R5 and R6 are independently hydrogen atom or phenyl, optionally substituted by fluor, chlorine or bromine; R4 is alkyl with C1-4; R8 and R9 are always phenyl and R11 and R12 are independently always alkyl with C1-3. These pyrrolcarboxamides are hypolipidemically and hypocholesterolemically effective and may be used as intermediates for production of trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-ones, which are also hypolipidemic and hypocholesterolemic agents.</p>
申请公布号 SK281983(B6) 申请公布日期 2001.09.11
申请号 SK19990001340 申请日期 1994.02.24
申请人 WARNER-LAMBERT COMPANY 发明人 BUTLER DONALD EUGENE;LE TUNG VAN;NANNINGA THOMAS NORMAN
分类号 C07D295/18;A61K31/40;A61K31/4025;A61K31/4427;A61K31/443;A61K31/445;A61P3/06;C07C255/20;C07C255/26;C07C255/27;C07D207/06;C07D207/325;C07D207/34;C07D211/10;C07D211/16;C07D265/30;C07D319/04;C07D319/06;C07D401/06;C07D405/02;C07D405/06;C07D405/14;C07D491/113;(IPC1-7):C07D405/06;C07C255/13 主分类号 C07D295/18
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