发明名称 INHIBITING OXIDATIVE DEGRADATION OF PHARMACEUTICAL FORMULATIONS
摘要 The invention provides methods for inhibiting oxidative degradation of pharmaceutical formulations comprising at least one oxidation-susceptible active drug ingredient which methods comprise adding an oxidation-inhibiting amount of a ferrous ion source, preferably in the form of a pharmaceuticalexcipient, to the formulation. The invention further provides pharmaceutical formulations comprising at lea st one oxidation-susceptible active drug ingredient and an oxidation-inhibiting amount of a ferrous iron source, preferably in the form of a pharmaceuticalexcipient. The invention still further provides for the use d a ferrous ion source as an anti-oxidant in pharmaceutical formulations.
申请公布号 CA2339705(A1) 申请公布日期 2001.09.10
申请号 CA20012339705 申请日期 2001.03.08
申请人 PFIZER PRODUCTS INC. 发明人 WANG, HAI
分类号 A61K9/00;A61K47/02;A61K47/12;(IPC1-7):A61K31/439;A61K31/138;A61K31/40;A61K31/445;A61K31/495;A61K31/537 主分类号 A61K9/00
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