| 发明名称 |
MODULATION OF ENDOTHELIAL CELL SURFACE RECEPTOR ACTIVITY IN THE REGULATION OF ANGIOGENESIS |
| 摘要 |
A method of modulating angiogenesis in a vertebrate subject, the method comprising administering to the vertebrate subject an ECRTP/DEP-1 activity-modulating amount of a composition, whereby an ECRTP/DEP-1 within the vertebrate subject is contacted by the composition ; and modulating angiogenesis through the contacting of the ECRTP/DEP-1 with the composition. Optionally, the composition includes a monoclonal antibody which preferentially binds ECRTP/DEP-1. Methods for screening for modulators of ECRTP/DEP-1 are also disclosed. |
| 申请公布号 |
WO0164750(A2) |
申请公布日期 |
2001.09.07 |
| 申请号 |
WO2001US06178 |
申请日期 |
2001.02.27 |
| 申请人 |
VANDERBILT UNIVERSITY;DANIEL, THOMAS, O.;TAKAHASHI, TAKAMUNE;MERNAUGH, RAYMOND |
发明人 |
DANIEL, THOMAS, O.;TAKAHASHI, TAKAMUNE;MERNAUGH, RAYMOND |
| 分类号 |
G01N33/50;A61K35/74;A61K35/76;A61K38/00;A61K39/395;A61K48/00;A61P9/10;A61P17/06;A61P19/10;A61P27/02;A61P29/00;A61P35/00;A61P35/04;B01J20/281;C07K16/28;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;C12Q1/02;C12Q1/42;G01N30/88;G01N33/15;(IPC1-7):C07K16/00 |
主分类号 |
G01N33/50 |
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