| 摘要 |
<p>The present invention relates to dicarboxylato diammine platinum derivatives of formula (I), wherein R?1 and R2¿ are defined as in the description, to method for preparing them, and to antitumor chemical compositions comprising them. The compounds of formula (I) according to the invention have advantages as that they have low poison, wide spectrum of antitumor activity, high antitumor activity, good solvency in water and good stability in aqueous solution, and that they can selectively kill tumor cells while not harming normal cells. They are safe and effective antitumor agents.</p> |
