发明名称 METHODS FOR SELECTIVELY MODULATING SURVIVIN APOPTOSIS PATHWAYS
摘要 The present invention, based on the discovery of a new biological phenomena, provides methods and compositions for use in identifying agents that modulat e the phosphorylation of survivin, the interaction between survivin and p34cdc 2- cyclin B1 kinase complex, and the interaction between survivin and caspase-9 . Related methods and compositions can be used to modulate survivin regulated apoptosis.
申请公布号 CA2401607(A1) 申请公布日期 2001.09.07
申请号 CA20012401607 申请日期 2001.02.28
申请人 YALE UNIVERSITY 发明人 ALTIERI, DARIO C.
分类号 A61K31/711;A61K38/00;A61K45/00;A61K48/00;A61P35/00;A61P43/00;C07K16/18;C12N1/00;C12Q1/02;C12Q1/48;G01N33/15;G01N33/50;G01N33/53;G01N33/573;(IPC1-7):C12Q1/48;A61K49/00;C07K7/08;C07K14/81;C07K16/30;C12Q1/68;G01N33/68 主分类号 A61K31/711
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