BIOSYNTHETIC CARBOHYDRATE-DEFICIENT TRANSFERRIN REFERENCES

摘要

References, i.e., solutions of known concentration for use as controls, calibrators, or standards, for assays of carbohydrate-deficient transferrin in bodily fluids are obtained from units of bodily fluids from normal healthy individuals by digesting the transferrin in these units with exogenous neuraminidase to achieve concentrated CDT solutions, which are then added in preselected proportions to a base matrix to achieve target concentrations.