摘要 |
Novel compounds of the general formula (I) acting as ligands for the binding sites of sigma receptors; and drugs containing the compounds as the active ingredient, wherein X is alkyl, aryl, a heterocyclic group, or the like; Q i s - CH2-, -CO-, -O-, -CH(OR7)- (wherein R7 is hydrogen, alkyl, or the like), or the like; n is an integer of 0 to 5; R1 and R2 are each hydrogen, alkyl, or the like; and B is a group represented by the general formula (II) or (III) (wherein R3, R4, R5 and R6 are each hydrogen, halogeno, alkoxy, or the like; m is 1 or 2; and the ring (IV) is an aromatic heterocycle).
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申请人 |
MITSUBISHI PHARMA CORPORATION |
发明人 |
SAITO, KEN-ICHI;NAKAO, AKIRA;YAMABE, HARUKO;OKUYAMA, MASAHIRO;OOIZUMI, MITSURU |