发明名称 |
METHOD FOR PREPARING ANTI-MIF ANTIBODIES |
摘要 |
The specification provides methods of preparing high-affinity antibodies to a macrophage migration inhibitory factor (MIF) in animals in which the <i>MIF</i> gene has been homozygously knocked-out (MIF<-/->). Also provided are methods of preparing hybridomas which produce the anti-MIF antibodies, methods of administering the antibodies to treat inflammatory or cancerous conditions and/or diseases modulated by MIF, as well as compositions comprising said high-affinity anti-MIF antibodies.
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申请公布号 |
WO0164749(A2) |
申请公布日期 |
2001.09.07 |
申请号 |
WO2001US05933 |
申请日期 |
2001.02.26 |
申请人 |
IDEC PHARMACEUTICALS CORPORATION |
发明人 |
KLOETZER, WILLIAM, S.;HANNA, NABIL |
分类号 |
A01K67/00;A61K39/395;A61P13/12;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P31/04;A61P35/00;C07K14/52;C07K16/24;C12N15/85;C12P21/02;(IPC1-7):C07K16/00 |
主分类号 |
A01K67/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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