| 发明名称 |
INTRAVASCULAR DELIVERY OF NON-VIRAL NUCLEIC ACID |
| 摘要 |
Disclosed is a complex for providing nucleic acid expression in a cell. A polynucleotide and a polymer are mixed together to form the complex wherein the zeta potential of the complex is not positive. Then the complex is delivered to the cell wherein the nucleic acid is expressed.
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| 申请公布号 |
US2001019723(A1) |
申请公布日期 |
2001.09.06 |
| 申请号 |
US19990450315 |
申请日期 |
1999.11.29 |
| 申请人 |
MONAHAN SEAN D.;WOLFF JON A.;SLATTUM PAUL M.;HAGSTROM JAMES E.;BUDKER VLADIMIR G.;ROZEMA DAVID B. |
发明人 |
MONAHAN SEAN D.;WOLFF JON A.;SLATTUM PAUL M.;HAGSTROM JAMES E.;BUDKER VLADIMIR G.;ROZEMA DAVID B. |
| 分类号 |
A61K48/00;C12N5/08;(IPC1-7):A61K48/00;A61K9/48;C07H21/04;C12N15/85 |
主分类号 |
A61K48/00 |
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