发明名称 N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
摘要 Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 US2001020097(A1) 申请公布日期 2001.09.06
申请号 US19990280966 申请日期 1999.03.30
申请人 AUDIA JAMES E.;FOLMER BEVERLY K.;JOHN VARGHESE;LATIMER LEE H.;NISSEN JEFFREY S.;PORTER WARREN J.;THORSETT EUGENE D.;WU JING 发明人 AUDIA JAMES E.;FOLMER BEVERLY K.;JOHN VARGHESE;LATIMER LEE H.;NISSEN JEFFREY S.;PORTER WARREN J.;THORSETT EUGENE D.;WU JING
分类号 A61K31/00;A61K31/198;A61K31/223;C07C237/08;C07C237/10;C07C237/12;C07C271/22;C07D209/20;C07D215/38;C07D233/54;C07D233/61;C07D277/62;C07D277/82;(IPC1-7):C07D277/82 主分类号 A61K31/00
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