| 发明名称 |
Inhibition of angiogenesis by peptide analogs of high molecular weight kininogen domain 5 |
| 摘要 |
Peptide analogs of the high molecular weight kininogen domain 5 are potent inhibitors of angiogenesis. The peptides have the formulawhereinX1 is from zero to 25 amino acids;X2 is from zero to 60 amino acids.Methods of inhibiting endothelial cell proliferation and angiogenesis are provided.
|
| 申请公布号 |
US6284726(B1) |
申请公布日期 |
2001.09.04 |
| 申请号 |
US20000612126 |
申请日期 |
2000.07.07 |
| 申请人 |
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;DU PONT PHARMACEUTICALS COMPANY |
发明人 |
COLMAN ROBERT W.;MOUSA SHAKER A. |
| 分类号 |
A61K38/00;C07K14/81;(IPC1-7):A61K38/00;A61K38/04 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
