发明名称 Pharmaceutical compositions of meloxicam with improved solubility and bioavailability
摘要 Pharmaceutical compositions containing enolic carboxamide type antiinflammatory agent meloxicam that exhibit improved wettability, aqueous solubility, dissolution behaviour over a broad range of pH, and that are prepared by crystal structure modification of the drug through dry or wet mechanical homogenization with two further components-one of them is selected from a group of oligo-and dissolution improving, or alkalizing agent. The application of the formulations according to the present invention results in an improved biovailability and effectiveness of meloxicam.
申请公布号 US6284269(B1) 申请公布日期 2001.09.04
申请号 US20000486463 申请日期 2000.05.10
申请人 HEXAL AG 发明人 STRUENGMANN ANDREAS;FREUDENSPRUNG BRIGITTE;KLOKKERS KARIN
分类号 A61K9/02;A61K9/00;A61K9/06;A61K9/14;A61K9/16;A61K9/20;A61K9/46;A61K31/54;A61K31/5415;A61K47/10;A61K47/26;A61K47/38;A61K47/40;A61K47/48;(IPC1-7):A61K9/62 主分类号 A61K9/02
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