发明名称 |
Cell culture module having sinusoid-like structure |
摘要 |
The present invention provides a module for cell culture comprising a structure comprising hollow fibers and at least two spacers, wherein the spacers have small pores regularly arranged therein and the hollow fibers pass through the small pores and are arranged regularly at a very small distance, a hybrid artificial liver module wherein hepatocytes are immobilized in this module, and a method of cell culture wherein cells are immobilized in the lumen or extra-fiber space of the module of this module by the use of a centrifugal force and wherein the immobilized cells are cultured. The present invention also provides a method for cell culture wherein hepatocytes are cultured in a culture medium containing DMEM as a basal medium.
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申请公布号 |
US6284451(B1) |
申请公布日期 |
2001.09.04 |
申请号 |
US20000648027 |
申请日期 |
2000.08.25 |
申请人 |
TOYO BOSEKI KABUSHIKI KAISHA;FUNATSU KAZUMORI |
发明人 |
FUNATSU KAZUMORI;IJIMA HIROYUKI;NAKAZAWA KOUJI;MIZUMOTO HIROSHI |
分类号 |
C12M3/00;A61M1/36;B01D63/02;C12M3/06;C12N5/06;(IPC1-7):A61F2/04 |
主分类号 |
C12M3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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