| 摘要 |
Disclosed are compounds of the formula:or pharmaceutically acceptable salts thereof, wherein:A is (un)substituted alkylene;R1 and R2 are the same or different and represent hydrogen, halogen, alkyl, alkoxy, alkylthio, hydroxy, (un)substitutedamino, cyano, nitro, sulfonamide, trifluoromethyl or trifluoromethoxy;R3, R4, R5, R6, and R8 are independently hydrogen or alkyl; andX is sulfur, oxygen or NR7 where R8 is defined herein;m is an integer chosen from 0, 1 or 2; andAr is an aryl or heteroaryl group as further defined herein,which compounds are useful for the treatment and/or prevention of neuropsychological disorders including, but not limited to, schizophrenia, mania, dementia, depression, anxiety, compulsive behavior, substance abuse, Parkinson-like motor disorders and motion disorders related to the use of neuroleptic agents.
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