发明名称 Antagonistic selective binding agents of osteoprotegerin binding protein
摘要 Selective binding agents of osteoprotegerin binding protein (OPGbp) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to OPGbp and may be used to prevent or treat conditions relating to loss of bone mass. Nucleic acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provided.
申请公布号 AU3868001(A) 申请公布日期 2001.09.03
申请号 AU20010038680 申请日期 2001.02.23
申请人 AMGEN INC 发明人 RAJENDRA V. DESHPANDE;ANNA HITZ;WILLIAM J BOYLE;JOHN KEVIN SULLIVAN
分类号 C12N15/09;A61K38/22;A61K39/395;A61K45/00;A61P3/14;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/08 主分类号 C12N15/09
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