Analysis of biological targets using a biochip comprising a fluorescent marker

摘要

Analytical support (A), which is fixed to a carrier, comprises many oligonucleotides (ON), each of which is labeled by a fluorescent compound (I), the fluorescence of which varies when ON hybridizes to its complement, is new. Independent claims are also included for the following: (1) the quality control of (A) in which the amounts and positions of the fixed ONs are determined by measuring the fluorescence from (I); an (2) analyzing biological targets by applying them to (A) and identifying those ON which have hybridized by measuring fluorescence from each ON before and after contact with the targets.