COMBINED USE OF INTERLEUKIN 10 AND METHOTREXATE FOR IMMUNO-MODULATORY THERAPY

摘要

A combination of interleukin (10) and methotrexate is used to suppress autoimmune diseases including arthritis and psoriasis. It has been discovered that administration of a combination of interleukin (10) and methotrexate causes suppression of T cell proliferation. Concurrent use of both agents avoids the toxicity associated with higher doses of methotrexate.