发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALOPECIA AND OTHER DISORDERS OF THE PILOSEBACEOUS APPARATUS |
摘要 |
Insulin sensitivity increasing substances (ISIS), including but not limited to D-chiro-inositol, thiazolidinedione and derivatives, and biguanides, are useful in the treatment of hair loss and other disorders of the pilosebaceous apparatus (hirsutism, acne, etc.) associated with conditions of excess insulin and/or insulin resistance. The treatment comprises administering to a mammal, such as a human, at least one ISIS either alone or in combination with at least one agent, such as an androgen receptor blocker (ARB) and/or a steroid enzyme inhibitor or inducer (STI). Additionally, an activity enhancing agent may be included for topical administration.
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申请公布号 |
WO0162237(A2) |
申请公布日期 |
2001.08.30 |
申请号 |
WO2001US05653 |
申请日期 |
2001.02.23 |
申请人 |
ORENTREICH FOUNDATION FOR THE ADVANCEMENT OF SCIENCE, INC.;KRAJCIK, ROZLYN, A.;ORENTREICH, NORMAN |
发明人 |
KRAJCIK, ROZLYN, A.;ORENTREICH, NORMAN |
分类号 |
A61K31/00;A61K31/155;A61K31/426;A61K31/427;A61K31/4439;A61K31/7004;A61K45/06;A61P17/10;A61P17/14;(IPC1-7):A61K31/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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