| 发明名称 |
NOVEL COMPOSITIONS AND USES OF DICTYOSTATIN COMPOUNDS |
| 摘要 |
Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug - resistant cancers, autoimmune disorders, and inflammatory diseases.
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| 申请公布号 |
CA2400896(A1) |
申请公布日期 |
2001.08.30 |
| 申请号 |
CA20012400896 |
申请日期 |
2001.02.26 |
| 申请人 |
HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. |
发明人 |
POMPONI, SHIRLEY A.;CUMMINS, JENNIFER L.;WRIGHT, AMY E.;LONGLEY, ROSS E.;ISBRUCKER, RICHARD A. |
| 分类号 |
A61K31/365;A61K31/366;A61K35/56;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07K14/435;(IPC1-7):A61P35/00;A61P37/00 |
主分类号 |
A61K31/365 |
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