发明名称 |
COMPOSITIONS, SYSTEMS, AND METHODS FOR CREATING IN SITU, CHEMICALLY CROSS-LINKED, MECHANICAL BARRIERS |
摘要 |
A biocompatible and biodegradable barrier material is applied to a tissue region, e.g., to seal a vascular puncture site. The barrier material comprises a compound, which is chemically cross-linked without use of an enzyme to form a non-liquid mechanical matrix. The compound preferably includes a protein comprising recombinant or natural serum albumin, which is mixed with a polymer that comprises poly(ethylene) glycol (PEG), and, most preferably, a multi-armed PEG polymer.
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申请公布号 |
US2001018598(A1) |
申请公布日期 |
2001.08.30 |
申请号 |
US19980188083 |
申请日期 |
1998.11.06 |
申请人 |
CRUISE GREGORY M.;HNOJEWYJ OLEXANDER |
发明人 |
CRUISE GREGORY M.;HNOJEWYJ OLEXANDER |
分类号 |
A61B17/00;A61B17/34;A61B18/14;A61K31/77;A61K38/00;A61L24/00;A61L24/04;A61L24/10;A61L31/00;A61M25/06;A61P7/04;(IPC1-7):A61D1/00;A61B17/08 |
主分类号 |
A61B17/00 |
代理机构 |
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地址 |
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