PROCESS FOR PRODUCING AVERMECTIN DERIVATIVE

摘要

22,23-Dihydroavermectin B1a, which is useful in drugs, veterinary drugs and pesticides, can be produced by direct fermentation. Thus, the troublesome an d difficult industrial steps of purifying avermectin B1a and chemically modifying avermectin B1a involved in the conventional are can be omitted and therefore 22,23-dihydroavermectin B1a can be industrially produced while largely saving the cost and time. Moreover, a preparation containing 22,23- dihydroavermectin B1a alone, which is highly efficacious as a drug, can be produced.