| 发明名称 |
Therapeutic compound-fatty acid conjugates |
| 摘要 |
A therapeutic compound of the chlorambucil family conjugated to two or three acyl groups derived from fatty acids. The compound has the following formula.in which X is chlorambucil, Y is an optional spacer group, AA is an amino acid, B is H or CH2O-R3, and n is a number from 0 to 3. X is linked to Y via the carboxyl group. R1, R2 and R3 are as defined by the present specification.
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| 申请公布号 |
US6281376(B1) |
申请公布日期 |
2001.08.28 |
| 申请号 |
US19990289715 |
申请日期 |
1999.04.12 |
| 申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION |
发明人 |
WHITTAKER ROBERT GEORGE;BENDER VERONIKA JUDITH;REILLY WAYNE GERRARD;MOGHADDAM MINOO |
| 分类号 |
C07K14/775;A61K31/57;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7072;A61K38/00;A61K38/05;A61K47/48;A61P25/04;A61P29/00;A61P31/12;A61P37/04;C07C237/22;C07D475/08;C07D489/02;C07H19/04;C07H19/06;C07J5/00;C07J41/00;C07K5/00;C07K5/065;C07K7/06;(IPC1-7):C07C57/00 |
主分类号 |
C07K14/775 |
| 代理机构 |
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