发明名称 Cycloalkyl inhibitors of protein farnesyltransferase
摘要 Novel inhibitors of protein farnesyltransferase enzymes are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer, restenosis, atherosclerosis, psoriasis and endometriosis.
申请公布号 US6281194(B1) 申请公布日期 2001.08.28
申请号 US19990319422 申请日期 1999.06.02
申请人 WARNER-LAMBERT COMPANY 发明人 DOHERTY ANNETTE M.;KALTENBRONN JAMES S.;LEONARD DANIELE M.;MCNAMARA DENNIS J.
分类号 C12N9/99;A61K38/00;A61K38/55;A61P9/00;A61P17/06;A61P35/00;C07K5/06;C07K5/078;(IPC1-7):C07K5/078 主分类号 C12N9/99
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