发明名称 |
Use of mCRP to enhance immune responses |
摘要 |
The invention provides a method of enhancing an immune response to an immunogen in an animal. The method comprises administering to the animal an effective amount of the immunogen and an effective amount of a modified C-reactive protein (mCRP) or a mutant-mCRP. The invention also provides a vaccine and a method of producing this vaccine. The vaccine comprises an immunogen and an mCRP or a mutant-mCRP in a pharmaceutically-acceptable vehicle. The invention further provides a kit for immunizing an animal to an immunogen comprising (1) a container holding the immunogen and a container holding an mCRP or a mutant-mCRP or (2) a container holding the immunogen and an mCRP or a mutant-mCRP. The invention also provides a method of elicing an immune response to a hapten in an animal. The method comprises administering to the animal an effective amount of the hapten in association with an an effective amount of an mCRP or a mutant-mCRP. The invention further provides a vaccine and a method of producing this vaccine. The vaccine comprises a hapten and an mCRP or a mutant-mCRP in a pharmaceutically-acceptable vehicle. Finally, the invention provides a kit for immunizing an animal to a hapten comprising a container holding the hapten and an mCRP or a mutant-mCRP.
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申请公布号 |
US6280743(B1) |
申请公布日期 |
2001.08.28 |
申请号 |
US20000568212 |
申请日期 |
2000.05.09 |
申请人 |
IMMTECH INTERNATIONAL, INC. |
发明人 |
POTEMPA LAWRENCE A.;RADOSEVICH JAMES A. |
分类号 |
A61K35/00;A61K39/08;A61K39/39;A61P37/04;(IPC1-7):A61K39/00 |
主分类号 |
A61K35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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