发明名称 Antithrombotic agent and anti-von willebrand factor monoclonal antibody
摘要 A monoclonal antibody, which has reactivity with human von Willebrand factor, which has action to inhibit RIPA (ristocetin-induced platelet aggregation), BIPA (botrocetin-induced platelet aggregation), and SIPA (shear stress-induced platelet aggregation) of human platelet, and which does not express bleeding action in an medicinally effective dose to exhibit antithrombotic action, is used as an active ingredient of an antithrombotic agent.
申请公布号 US6280731(B1) 申请公布日期 2001.08.28
申请号 US19990299016 申请日期 1999.04.26
申请人 AJINOMOTO CO., INC. 发明人 NAGANO MITSUYO;YAMAMOTO HIROSHI;KITO MORIKAZU;YOSHIMOTO RYOTA;KOBAYASHI TSUYOSHI
分类号 A61K38/00;C07K16/36;C12N5/20;C12P21/08;(IPC1-7):A61K39/395 主分类号 A61K38/00
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