发明名称 Hetero-polysaccharide conjugate and methods of making and using the same
摘要 Disclosed and claimed are: a composition including at least one glycosaminoglycan, e.g., CIS, and at least one alginate, e.g., sodium alginate, wherein:the at least one glycosaminoglycan and/or the algninate are cross-linked or polymerized, e.g., the alginate is cross-linked or polymerized, for instance by addition of an inorganic salt, such as a calcium salt; orthe at least one glycosaminoglycan and the alginate are covalently bound, e.g., by means of a coupling reaction involving a linker molecule such as DVS; orthe at least one glycosaminoglycan and/or the algninate are cross-linked or polymerized, e.g., the alginate is cross-linked or polymerized, for instance by addition of an inorganic salt, such as a calcium salt, and the at least one glycosaminoglycan and the alginate are covalently bound, e.g., by means of a coupling reaction involving a linker molecule such as DVS, and the covalent binding can have been performed prior to cross-linking or polymerizing or vice versa; and,gels comprising the composition; mixtures of such gels or of at least one such gel and at least one such composition; and,methods for making and using such compositions and gels, including products therefrom such as "paints", sprays, matrices, beads, microcapsules.
申请公布号 US6281341(B1) 申请公布日期 2001.08.28
申请号 US19970877682 申请日期 1997.06.17
申请人 BIOMM, INC. & UNIVERSITY OF MIAMI 发明人 MARES-GUIA MARCOS;RICORDI CAMILLO
分类号 A61K9/16;A61K9/50;A61K9/70;A61L17/14;A61L27/38;C08L5/04;(IPC1-7):C08B37/04;A01N63/00;A61K9/14 主分类号 A61K9/16
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