发明名称 TRICYCLIC CONDENSED HETEROCYCLIC COMPOUND, METHOD FOR PRODUCING THE SAME AND MEDICAMENT USING THE SAME
摘要 PROBLEM TO BE SOLVED: To provide a new compound having excellent antagonism against corticotropin-releasing factor receptors. SOLUTION: This new compound is shown by the formula [wherein, A and B are each a group of the formula (CR1R2)m (wherein, R1 and R2 are each a 1-6C alkyl or the like) or the formula NR3 (wherein, R3 is H or the like) or the like; E and G are each a group of the formula(CR6R7)p (wherein, R6 and R7 are each H or the like; and p is an integer of 0, 1 or 2) or the like; J is a carbon or nitrogen atom substituted with (halogen-substituted) 1-6C alkyl or the like, or the like; K and L are each a carbon or nitrogen atom; M is H, a halogen atom, (substituted) 1-6C alkyl or the like; and partial structure denotes a single or double bond]. The other objective pharmacologically acceptable salt thereof and hydrates thereof are also provided, respectively.
申请公布号 JP2001233876(A) 申请公布日期 2001.08.28
申请号 JP20000375811 申请日期 2000.12.11
申请人 EISAI CO LTD 发明人 HIBI SHIGEKI;HOSHINO TAKEHISA;YOSHIUCHI TATSUYA;SHIN MITSUTAMA;KIKUCHI KOICHI;SOEJIMA HIROYOSHI;TABATA MUTSUKO;TAKAHASHI YOSHINORI;SHIBATA HISASHI;HIDA TAKAYUKI;HIRAKAWA TETSUYA;INO MITSUHIRO
分类号 C07D487/14;A61K31/4375;A61K31/4745;A61K31/519;A61K31/52;A61K31/55;A61P1/00;A61P1/08;A61P1/14;A61P3/04;A61P3/10;A61P5/14;A61P11/06;A61P13/08;A61P15/08;A61P15/10;A61P15/12;A61P17/14;A61P19/10;A61P21/00;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P27/06;A61P31/18;A61P37/00;A61P37/08;A61P43/00;C07D471/04;C07D471/14;C07D487/04;C07D491/147;C07D495/14;(IPC1-7):C07D487/14;A61K31/437;A61K31/474 主分类号 C07D487/14
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