发明名称 |
TH1 inducing natural adjuvant for heterologous antigens |
摘要 |
The present invention relates to the use of the major OprI lipoprotein of Pseudomonas aeruginosa to elicit a Type-1 immune response towards a heterologous antigen. The invention relates specifically to the use of OprI-antigen fusion proteins to elicit the Type-1 response. More particularly, the present invention is directed to pharmaceutical formulations comprising OprI and/or OprI fusion proteins, optionally together with a suitable excipient, to stimulate the Th1 dependent, cellular immune response. |
申请公布号 |
AU4831401(A) |
申请公布日期 |
2001.08.27 |
申请号 |
AU20010048314 |
申请日期 |
2001.02.13 |
申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW |
发明人 |
HILDE REVETS;PIERRE CORNELIS;PATRICK DE BAETSELIER |
分类号 |
A61K39/39;A61P37/04;C07K14/21;C07K14/44;C07K16/10 |
主分类号 |
A61K39/39 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|