| 摘要 |
Use of a compound with general formula (I) wherein R' and R'' are individually chosen from thiophene, phenyl and phenyl substituted with at least one group selected from amino, hydroxy and carboxy, or of a pharmaceutically acceptable salt, solvate or isomer thereof, for the manufacture of a medicament for potentiating the neurotrophic effects on mammalian neurons of the neurotrophic factor neurotrophin-3 (NT-3), or for stimulating neural stem cell growth and differentiation in combination with the neurotrophic factor neurotrophin-3 (NT-3). The invention further relates to a method for potentiating the neurotrophic effects of NT-3 on mammalian neurons, as well as a method for stimulating neural stem cell growth and differentiation in combination with NT-3. |
