发明名称 Modification of biopolymers for improved drug delivery
摘要 A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved <i>in vivo</i> stability and activity, and can be targeted to a variety of cells, tissues and organs.
申请公布号 AU3834601(A) 申请公布日期 2001.08.27
申请号 AU20010038346 申请日期 2001.02.15
申请人 GENZYME CORPORATION 发明人 PERICLES CALIAS;ROBERT J. MILLER
分类号 A61K47/48;A61P1/16;A61P7/00;A61P35/00 主分类号 A61K47/48
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