发明名称 OLIGONUCLEOTIDES IMMUNOSTIMULANTS
摘要 The invention concerns an oligonucleotide capable of stimulating human cells of an immune system, characterised in that it comprises at least a nucleotide sequence corresponding to formula 5' GAGAATTCTTTACCTTTTAT3', wherein T represents Thymine, A Adenine, C Cystosine, and G Guanine, and it does not include CG dinucleotide wherein the Cytosine C is unmethylated. Said oligonucleotide is particularly useful as vaccine adjuvant.
申请公布号 FR2805265(A1) 申请公布日期 2001.08.24
申请号 FR20000002057 申请日期 2000.02.18
申请人 AVENTIS PASTEUR 发明人 BACHY MONIQUE;TRANNOY EMMANUELLE;SODOYER REGIS
分类号 A61P37/04;C12N15/117;(IPC1-7):C07H21/00;C07H21/04;A61K31/708;A61K39/39 主分类号 A61P37/04
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