发明名称 PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID delta RECEPTOR AGONISTS
摘要 Drugs useful in the prevention and/or treatment of nervous system diseases, containing as the active ingredient compounds of the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein X is a group represented by the general formula (II), (III), (IV), (V) or (VI); A is a saturated or unsaturated 3- to 6-membered carbocyclic group or the like; B is CH2 or the like; n is 0 to 2; R<1> is hydrogen, halogeno, or the like; R<2>, R<3>, and R<7> to R<14> are each hydrogen, optionally substituted lower alkyl, or the like; R<4> is hydrogen, optionally substituted lower alkyl, or the like; R<5> is hydrogen, halogeno, or the like; and R<6> is a saturated or unsaturated mono- or bicyclic carbocyclic group or the like, or alternatively, R<5> and R<6>, R<7> and R<8>, R<9> and R<10>, and/or R<11> and R<12> may be united to form a cyclic structure.
申请公布号 WO0160796(A1) 申请公布日期 2001.08.23
申请号 WO2001JP01116 申请日期 2001.02.16
申请人 MEIJI SEIKA KAISHA, LTD.;TSUSHIMA, MASAKI;TADAUCHI, KAORI;ASAI, KENJI;MIIKE, NAOKO;IMAI, MASAKO;KUDO, TOSHIAKI 发明人 TSUSHIMA, MASAKI;TADAUCHI, KAORI;ASAI, KENJI;MIIKE, NAOKO;IMAI, MASAKO;KUDO, TOSHIAKI
分类号 A61K31/438;A61K31/445;A61K31/451;A61K31/454;A61K31/4709;A61K31/517;A61K31/536;C07D211/14;(IPC1-7):C07D211/14;C07D221/20;C07D401/04;C07D405/14;C07D413/04;C07D417/04;C07D471/10;C07D471/20;A61K31/470;A61P43/00;A61P25/00;A61P25/18;A61P25/24;A61P25/08;A61P25/28;A61P25/16;A61P25/04;A61P9/10 主分类号 A61K31/438
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