发明名称 Dipeptide nitrile cathepsin K inhibitors
摘要 Dipeptide nitrile Cathepsin K inhibitors of formula I, and pharmaceutically acceptable salts or esters thereof In which R1 and R2 are independently H or C1-C7lower alkyl, or R1 and R2 together with the carbon atom to which they are attached form a C3-C8cycloalkyl ring, and Het is an optionally substituted nitrogen-containing heterocyclic substituent, are provided, useful e.g. for therapeutic or prophylactic treatment of a disease or medical condition in which cathepsin K is implicated.
申请公布号 US2001016207(A1) 申请公布日期 2001.08.23
申请号 US20010778302 申请日期 2001.02.07
申请人 MISSBACH MARTIN 发明人 MISSBACH MARTIN
分类号 C07D295/14;A61K31/445;A61K31/451;A61K31/495;A61P1/02;A61P3/14;A61P9/00;A61P9/10;A61P11/00;A61P19/00;A61P19/02;A61P19/10;A61P21/04;A61P29/00;A61P33/00;A61P33/06;A61P35/00;A61P37/06;A61P43/00;C07D211/26;C07D211/34;C07D295/155;(IPC1-7):A61K31/496;A01N43/40;C07D241/04;C07D295/00;A61K9/20 主分类号 C07D295/14
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