发明名称 PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID .DELTA. RECEPTOR AGONISTS
摘要 Drugs useful in the prevention and/or treatment of nervous system diseases, containing as the active ingredient compounds of the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein X is a group represented by the general formula (II), (III), (IV), (V) or (VI); A is a saturated or unsaturated 3- to 6-membered carbocyclic group or the like; B i s CH2 or the like; n is 0 to 2; R1 is hydrogen, halogeno, or the like; R2, R3, and R7 to R14 are each hydrogen, optionally substituted lower alkyl, or the like; R4 is hydrogen, optionally substituted lower alkyl, or the like; R5 is hydrogen, halogeno, or the like; and R6 is a saturated or unsaturated mono- or bicyclic carbocyclic group or the like, or alternatively, R5 and R6, R7 and R8, R9 and R10, and/or R11 and R12 may be united to form a cyclic structure.
申请公布号 CA2400640(A1) 申请公布日期 2001.08.23
申请号 CA20012400640 申请日期 2001.02.16
申请人 MEIJI SEIKA KAISHA, LTD. 发明人 TSUSHIMA, MASAKI;IMAI, MASAKO;KUDO, TOSHIAKI;ASAI, KENJI;TADAUCHI, KAORI;MIIKE, NAOKO
分类号 A61K31/438;A61K31/445;A61K31/451;A61K31/454;A61K31/4709;A61K31/517;A61K31/536;C07D211/14;(IPC1-7):C07D211/14;A61P25/00;A61P43/00;C07D401/04;C07D413/04;C07D417/04;A61P25/04;A61P25/08;C07D471/10;A61P9/10;C07D405/14;A61P25/16;A61P25/18;C07D221/20;C07D471/20;A61P25/24;A61P25/28;A61K31/470 主分类号 A61K31/438
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