发明名称 |
NOVEL ECHINOCANDIN DERIVATIVES, PREPARATION METHOD AND USE THEREOF AS FUNGICIDES |
摘要 |
The invention concerns compounds of general formula (I) wherein: R1 represents a hydrogen atom, a hydroxy radical, Ob or Ncd; A represents an oxygen atom, a CH2 radical or a NH radical; B represents the radical of a steroid; R3 represents a hydrogen atom, a methyl or hydroxyl radical; R4 represents a hydrogen atom or a hydroxyl radical; T represents a hydrogen atom, a methyl radical, a CH1CONH2, CH2CN radical, a (CH2)2NH2 or (CH2)2Nalk<+>X<->radical; X being a halogen atom and alc an alkyl radical; Y represents a hydrogen atom, a hydroxyl radical or a halogen atom or a OSO3H radical; W represents a hydrogen atom or a OH radical; Z represents a hydrogen atom or a methyl radical. The compounds of formula (I) exhibit antifungal properties.
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申请公布号 |
WO0160845(A1) |
申请公布日期 |
2001.08.23 |
申请号 |
WO2001FR00419 |
申请日期 |
2001.02.14 |
申请人 |
AVENTIS PHARMA S.A.;COURTIN, OLIVIER;DUSSARAT, ARLETTE;MELON-MANGUER, DOMINIQUE;SCHIO, LAURENT |
发明人 |
COURTIN, OLIVIER;DUSSARAT, ARLETTE;MELON-MANGUER, DOMINIQUE;SCHIO, LAURENT |
分类号 |
A61K38/00;A61P31/10;C07K7/56;(IPC1-7):C07K7/56;A61K38/12 |
主分类号 |
A61K38/00 |
代理机构 |
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